Clonal evolution: multiregion sequencing of esophageal adenocarcinoma before and after chemotherapy.
نویسندگان
چکیده
It is possible to decipher the clonal architecture of a tumor and the sequence in which cancer clones acquire genomic alterations through multiregion sequencing (M-seq). Serial evaluation of tumor specimens through M-seq can provide valuable information on the molecular basis of resistance to therapy.
منابع مشابه
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ورودعنوان ژورنال:
- Cancer discovery
دوره 5 8 شماره
صفحات -
تاریخ انتشار 2015